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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
21.52
Human Site:
Y478
Identified Species:
36.41
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
Y478
A
K
D
K
L
R
S
Y
A
S
R
I
Q
R
P
Chimpanzee
Pan troglodytes
XP_508221
618
67613
Y568
A
K
D
K
L
R
S
Y
A
S
R
I
Q
R
P
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
R441
D
F
A
K
S
I
T
R
P
F
S
V
Y
F
N
Dog
Lupus familis
XP_855547
495
55650
Y445
A
K
D
K
L
R
N
Y
A
S
R
I
Q
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
Y448
A
K
D
K
L
R
N
Y
A
S
R
I
Q
R
P
Rat
Rattus norvegicus
P04177
498
55948
Y448
A
K
D
K
L
R
N
Y
A
S
R
I
Q
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
F518
A
K
E
K
V
R
N
F
A
S
T
I
P
R
P
Chicken
Gallus gallus
P70080
445
51121
R396
E
F
A
K
T
I
K
R
P
F
G
V
K
Y
N
Frog
Xenopus laevis
Q92142
481
55388
R432
E
F
A
K
T
I
Q
R
P
F
G
L
K
Y
N
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
V440
T
E
K
L
R
T
Y
V
T
R
I
K
R
P
F
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
A427
K
L
R
R
Y
S
A
A
I
K
R
P
F
A
V
Fruit Fly
Dros. melanogaster
P18459
579
65977
W526
A
K
D
K
F
R
R
W
V
S
T
M
S
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
R408
S
W
A
A
T
I
N
R
P
F
Q
I
R
Y
N
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
Y472
A
Q
S
K
L
R
L
Y
A
M
K
M
A
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
60
6.6
6.6
0
6.6
53.3
N.A.
6.6
53.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
86.6
20
20
13.3
20
66.6
N.A.
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
29
8
0
0
8
8
50
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
15
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
22
0
0
8
0
0
8
0
29
0
0
8
8
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
29
0
0
8
0
8
50
0
0
0
% I
% Lys:
8
50
8
79
0
0
8
0
0
8
8
8
15
0
0
% K
% Leu:
0
8
0
8
43
0
8
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% M
% Asn:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
29
% N
% Pro:
0
0
0
0
0
0
0
0
29
0
0
8
8
8
58
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
8
0
36
0
0
% Q
% Arg:
0
0
8
8
8
58
8
29
0
8
43
0
15
58
0
% R
% Ser:
8
0
8
0
8
8
15
0
0
50
8
0
8
0
0
% S
% Thr:
8
0
0
0
22
8
8
0
8
0
15
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
8
8
0
0
15
0
0
8
% V
% Trp:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
43
0
0
0
0
8
22
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _